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The oral microbiome: resistance genes and rheumatism 8 April 2026 12:15 - 13:00

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How functional and genetic characteristics of the oral microbiome contribute to oral diseases and systemic autoimmunity.

On April 8, Professor of Molecular Microbiology Thuy Do (School of Dentistry, University of Leeds, UK) will give a lecture at ACTA on the oral microbiome, from the spread of resistance genes to its association with rheumatoid arthritis. Rheumatoid arthritis is a form of rheumatism and a chronic inflammatory disease of the joints.

New research shows that changes in the bacteria and genetic characteristics of the mouth may play an important role in the development of oral diseases as well as other conditions in the body. For example, certain patterns in oral bacteria and their resistance to antibiotics appear to be good predictors of periodontitis (severe gum inflammation). In addition, there are indications that processes in the gums may already play a role in the development of rheumatoid arthritis—a chronic inflammatory disease of the joints—before the first symptoms appear.

About The oral microbiome: resistance genes and rheumatism

Starting date

  • 8 April 2026

Time

  • 12:15 - 13:00

Location

  • Kleine collegezaal OZ-04

Organised by

  • Dongmei Deng (ACTA, Preventive Dentistry)

Language

  • English

Thuy Do

Thuy Do

Professor Thuy Do is a leading expert in oral microbiology at the School of Dentistry, University of Leeds. She gained an Undergraduate degree in Biochemistry from the University of Strasbourg, France. She also holds a BSc in Food Science and Nutrition, and an MSc in Analytical Chemistry. She later obtained a PhD in Microbiology from De Montfort University, Leicester, and spent eight years working as a post-doctoral researcher at King’s College London, Guy’s Hospital Dental Institute. In 2012, she moved to Leeds to take a lectureship in Microbiology at the University of Leeds, School of Dentistry, where she teaches microbiology to Dental Surgery students and supervises Undergraduate and Postgraduate students. She is engaged in numerous academic and industrial research projects which form part of national and international collaborations. Her research interests include the investigation of the functional biology governing complex interactions within oral biofilms, to better understand the mechanisms of dysbiosis (microbial imbalance) and host-microbiome interactions, with the potential to enhance future diagnostic tools for oral and systemic health. Her expertise spans bacteriology, and metagenomics and metatranscriptomics. 

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