A high-throughput biofilm model capable of producing up to 75 identical biofilms
- Excellent for longitudinal studies
- Wash-out periods
- Biofilm thickness is pre-set at: 100 – 200 – 300 – 400 – 500 – 600 µm
- Various substrates ø 5mm possible; teflon, enamel, dentine, perspex
- Used for single species, multi-species and microcosm biofilms
- Using our unique reciprocal mode, inter-experimental controls are possible.
- During treatment wash-out periods are present
Output parameters:
- Composition:
- Colony forming units
- Microbiome analysis
- Quantitative PCR
Metabolic activity:
- Organic acid production
- Ammonium production
- Arginine catabolism
- pH profiling
Effect on hard tissues:
- Transversal microradiography
- Fluoride content
References
- Volgenant et al. (2016) Red fluorescent biofilm: the thick, the old, and the cariogenic. J. Oral. Microbiol. https://doi.org/10.3402/jom.v8.30346
More information
Contact Michel Hoogenkamp through M.Hoogenkamp@acta.nl.