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pH-cycling

De- and/or remineralisation studies.

After consumption of carbohydrates the pH of dental plaque is temporarily reduced and causes dissolution of dental hard tisses. pH-cycling is a technique to mimic these pH-fluctuations and their effect on dental hard tissues (enamel and dentine). This technique can be used to test the efficacy of products that influence de- and remineralization of dental hard tissues (i.e. toothpastes, topical applications, oral rinses). ACTA has developed a pH-cycling robot that will cycle 45 specimens simultaneously.

References

  • Elevated fluoride products enhance remineralization of advanced enamel lesions.  ten Cate JM, Buijs MJ, Miller CC, Exterkate RA. J Dent Res. 2008 Oct;87(10):943-7.
  • Effects of a new titanium fluoride derivative on enamel de- and remineralization. Exterkate RA, Ten Cate JM. Eur J Oral Sci. 2007 Apr;115(2):143-7.

More information

Contact Rob Exterkate through R.Exterkate@acta.nl.

Preventive Dentistry: Research on dental hard tissues