Sorry! De informatie die je zoekt, is enkel beschikbaar in het Engels.
This programme is saved in My Study Choice.
Something went wrong with processing the request.
Something went wrong with processing the request.

Oral Regenerative Medicine

Within this research programme, our scientists conduct research on the biological processes related to:
  • the adaptability (adaptation) and recovery of bone;
  • the supporting tissue around the teeth (periodontium);
  • and the biocompatibility of materials used by the dentist to restore dental function.

They are investigating, among other things, how to restore bone loss, for example caused by the gum disease periodontis or surgery. In addition, they research the quality and durability of materials, techniques and aids that should help restore this bone loss.

Oral Regenerative Medicine

  • Oral Radiology

    The research of the Department of Oral Radiology is focused on the development, improvement and efficacy of diagnostic imaging methods for the visualisation of normal and abnormal structures in the maxillofacial complex. This is realised from different perspectives including fundamental and applied (clinical) components. The research field of Diagnostic Imaging Methods at the department of Oral Radiology of ACTA comprises efficacy, accuracy and safety (radiation safety and patient/environmental safety) of diagnostic imaging. Nowadays 3D X-ray imaging using ConebeamCT plays an important role in dento-maxillo-facial imaging, and is therefore included in the research of the department. However, other techniques as infrared imaging, visual light (intraoral and extraoral 3D-video scanning) as well as ultrasound belong to the focus of our research group as well. Lastly, computer aided design (CAD) and computer aided / navigated surgery based on imaging methods also belong to our area of interest.

    Interested in our research?

    Researchers interested in a PhD project or general information on the research performed in our department should contact dr. W.E.R. Berkhout:

    All scientific publications (from 2009 until now) for Oral Radiology

  • Orofacial pain and dysfunction

    As one of the dental differentiations in the Netherlands, temporomandibular disorders (TMD) focuses on the diagnosis and treatment of pain and dysfunction of the masticatory system. Bruxism (i.e. tooth clenching and/or grinding) is thought to play an important aetiological role in TMD. Among others, bruxism may result in TMD pain and dental attrition. The close relationship between TMD, bruxism, and attrition necessitates an integrated approach to these clinical problems. This could be achieved through the multidisciplinary differentiation ‘oral kinesiology’, that covers not only the diagnosis and treatment of TMD and bruxism but also the restoration of worn dentitions. In addition, special attention is paid to the diagnosis and treatment of the obstructive sleep apnea syndrome due to its relation with the masticatory system. The Academic Centre for Dentistry Amsterdam offers dental practitioners a postgraduate training in oral kinesiology. This curriculum will ensure that specialised professionals (dentist–kinesiologists), who are able to approach the different aspects of oral kinesiology in an integrated manner, are available not only for the general dental practice but also for centres for special dental care and university departments. This will lead to improved care for patients, whose management is still frequently dispersed between various (dental) specialists.

    Overloading of the constituent tissues of the masticatory system, notably cartilage, bone, muscle tissue, periodontal tissues, and hard dental tissues due to bruxism (i.e., tooth grinding and clenching) and adverse oral habits (e.g., nail biting and excessive gum chewing) may lead to pain and dysfunction of the chewing apparatus. In turn, such conditions may yield risks for the individual’s general health and cognitive abilities. Within the framework of ORM, the causes, consequences, and management of pain and dysfunction of the masticatory system are studied in multiple international and multidisciplinary settings. Chewing, laughing, smiling, talking, yawning etc. are important movement functions of the human masticatory system. Sometimes patients are confronted with problems in performing these functions, which are related to a malfunction of the jaw muscles and/or the temporomandibular joint. This sub-programme studies the normal and disturbed functions of the jaw muscles and the temporomandibular joint, the factors that influence these functions and the treatment modalities that preserve or restore these functions.

    Some results obtained by the department of orofacial pain and dysfuncion
    • Mechanical overloading of the masticatory system was studied in a series of trials concerning bruxism (tooth grinding and clenching). Our insight into the etiology of bruxism was deepened on the basis of multiple epidemiological studies, while the management of the condition was tested with a series of randomized clinical trials (RCTs) using oral splints, psychological counseling, and medication at treatment modalities. The dental management of obstructive sleep apnea with oral appliances also yields a possible overload of the masticatory system. Both the short-term and the long-term usage of such appliances were assessed with polysomnographic techniques in RCTs, with continuous positive airway pressure as the usual treatment option for comparison.
    • Overloading of the masticatory system may lead to temporomandibular disorders (TMD). Clinical tests for the diagnosis TMD were further developed and tested for their reliability and validity. Especially the important influence of asking for familiar pain on the diagnostic accuracy of TMD pain is noteworthy. Studies to the diagnosis of pain in the masticatory system in persons with a dementia are currently ongoing. The importance of chewing in maintaining a good cognition was already demonstrated in a systematic review. The role of several psychosocial factors in the onset and maintenance of TMD pain was assessed in multiple questionnaire studies. Functional disturbances of the temporomandibular joint were studied in a series of experiments, in which the important role of mechanical loading on joint disc reduction was found.
    • Staff Orofacial Pain and Dysfunction

    All scientific publications (from 2009 until now) for Orofacial Pain and Dysfunction

  • Oral implantology

    The general mission of the programme is to improve the dentist’s knowledge of the treatment modalities that preserve or restore the patient’s function. This with special emphasis on Oral Implantology. The present research programme comprises three major research domains, Stimulation of bone growth around oral implants, oral implants used in prosthetic dentistry and peri-implantitis.

    All scientific publications (from 2009 until now) for Oral Implantology

  • Dental Materials Science

    The general objective of this programme is to predict and improve the clinical performance of dental restorative materials covering the complete range of materials involved in the procedures of creating restorations with direct or indirect techniques. Composition, structure and fabrication of the materials as well as their handling and application techniques are studied in vitro as well as in vivo. The increasing trend to replace the difficult and costly manual procedures by automated procedures with information technology is being studied on its merits. In particular the possible advantages of the automated production of indirect restorations by CAD/CAM technology are evaluated.

    All scientific publications (from 2009 until now) for Dental Materials Science

  • Oral Celbiology

    The research of “Bioengineering of Bone and Periodontium” of the Department of Oral Cell Biology studies the biological processes of functional adaptation and guided regeneration of bone and periodontium. Research focuses on fundamental aspects of mechanotransduction, and tissue engineering of bone, cartilage, and periodontium. The results are used in more applied research towards repair and regeneration of jawbone and periodontium, and prevention/treatment of infections around implants.

    All scientific publications (from 2009 until now) for Oral Cell Biology

  • Oral Maxillofacial Surgery

    The research of the Department of Oral and Maxillofacial Surgery/Oral Pathology of ACTA is focussed on early diagnosis of oral cancer and precancer, including cancer of the salivary glands, on surgical orthopedics of the maxillofacial skeleton and on maxillofacial implantology and reconstructive preprosthetic surgery. In addition research is performed on other aspects of oral and maxillofacial surgery, such as osteoradionecrosis and antithrombotic medication. The research is performed at VU Amsterdam and AMC locations of Amsterdam UMC.

  • Dental Education

    In the ACTA faculty of Dentistry research is performed on several aspects of education in dentistry. This includes research on the evaluation of courses within the curriculum, research on new teaching methods, such as the Objective Structured Clinical Examination (OSCE), and development and evaluation of a computed aided digital teaching system of pre-clinical skills (the Simodont), and comparison with biomedical education elsewhere in Europe.

    The input of academic personnel is limited to staff of the education institute, and to some staff members of the various departments.

    All scientific publications (from 2009 until now) for ACTA Education Institute